Alzheimer VS Hulbah
Hulbah (fenugreek
/ Trigonella foenum-graecum) mengandung kolin dan betakaroten cukup
tinggi yang sangat bermanfaat untuk mencegah dan mengatasi penyakit Alzheimer.
(Erabaru.2016).
Sebuah penelitian mendalam berhasil
membuktikan khasiat hulbah (fenugreek) untuk mencegah dan mengatasi Alzheimer.
Penelitian tersebut dilakukan oleh Prema, Justin Thenmozhi, Manivasagam,
Mohamed Essa dan Guillemin dengan judul Fenugreek
Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative
Stress, and Inflammation in a Rat Model of Alzheimer's Disease. yang
dipublikasikan pada laman https://www.ncbi.nlm.nih.gov/pubmed/28269780 .
Dalam abstraknya laporan tersebut meaporkan The result of the present study indicated that the
chronic administration of AlCl3 induced significant learning and memory
impairments, oxidative stress, and alterations in the protein immunocontent
patterns of IDE and CDK5 (enzymes involved in the metabolism of tau and amyloid
proteins), pTau, GFAP and Iba-1, IL-1β, IL-6, TNF-α, iNOS, NF-κB, COX-2, CDK5,
BDNF, and STAT3. Our behavioral, biochemical, and molecular studies revealed
that the co-administration of fenugreek seed powder significantly attenuated
the AlCl3 induced memory deficits, amyloid and tau pathology, oxidative stress,
and inflammation in AD rats could be due to the synergistic action of its
active components.
Sumber
Prem,dkk., “Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau
Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's
Disease”, 13:49 01 Juli 2017,
https://www.ncbi.nlm.nih.gov/pubmed/28269780
