Alzheimer VS Hulbah (Fenugreek)

Alzheimer VS Hulbah

Hulbah (fenugreek / Trigonella foenum-graecum) mengandung kolin dan betakaroten cukup tinggi yang sangat bermanfaat untuk mencegah dan mengatasi penyakit Alzheimer. (Erabaru.2016).

Sebuah penelitian mendalam berhasil membuktikan khasiat hulbah (fenugreek) untuk mencegah dan mengatasi Alzheimer. Penelitian tersebut dilakukan oleh Prema, Justin Thenmozhi, Manivasagam, Mohamed Essa dan Guillemin dengan judul Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's Disease. yang dipublikasikan pada laman https://www.ncbi.nlm.nih.gov/pubmed/28269780 .

Dalam abstraknya laporan tersebut meaporkan The result of the present study indicated that the chronic administration of AlCl3 induced significant learning and memory impairments, oxidative stress, and alterations in the protein immunocontent patterns of IDE and CDK5 (enzymes involved in the metabolism of tau and amyloid proteins), pTau, GFAP and Iba-1, IL-1β, IL-6, TNF-α, iNOS, NF-κB, COX-2, CDK5, BDNF, and STAT3. Our behavioral, biochemical, and molecular studies revealed that the co-administration of fenugreek seed powder significantly attenuated the AlCl3 induced memory deficits, amyloid and tau pathology, oxidative stress, and inflammation in AD rats could be due to the synergistic action of its active components.

Sumber

Erabaru. 2016. “Obat Dalam Lemari Dapur Anda”, 1:35 01 Juli 2017, http://www.erabaru.net/2016/06/16/obat-dalam-lemari-dapur-anda

Prem,dkk., “Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's Disease”, 13:49 01 Juli 2017,  https://www.ncbi.nlm.nih.gov/pubmed/28269780